Evolutionary Quantitative Genetics of Genomic Imprinting
نویسندگان
چکیده
منابع مشابه
Molecular Genetics of Genomic Imprinting
Keywords Androgenetic Embryo An embryo with two paternal genomes, and no maternal genome, produced by nuclear transplantation. Chromatin DNA packaged around nucleosomes. The degree of packaging differs between active (euchromatic) and inactive (heterochromatic) chromosomal regions.
متن کاملImplications of genomic imprinting for psychiatric genetics.
The genetics of psychiatric disease continues to be puzzling; what, for instance, really is the mode of transmission of schizophrenia? Is it polygenic (Gottesman & Shields, 1982)? Is it dominant but incompletely penetrant (Book, 1953), or partly dominant with incomplete penetrance (Slater, 1958); does it involve two loci with epistasis (Matthysse & Kidd, 1976), or is it none of these (O'Rourke ...
متن کاملImplications of genomic imprinting for psychiatric genetics
The genetics of psychiatric disease continues to be puzzling; what, for instance, really is the mode of transmission of schizophrenia? Is it polygenic (Gottesman & Shields, 1982)? Is it dominant but incompletely penetrant (Book, 1953), or partly dominant with incomplete penetrance (Slater, 1958); does it involve two loci with epistasis (Matthysse & Kidd, 1976), or is it none of these (O'Rourke ...
متن کاملEvolutionary Quantitative Genetics
I. Basic Statistical Machinery 1.1 Probabilities, Distributions, and Expectations 1.1 Discrete and Continuous Random Variables 1.1 Joint and Conditional Probabilities 1.2 Bayes’ Theorem 1.2 Expectations of Random Variables 1.3 The Normal Distribution 1.4 Covariances 1.4 The Normal Distribution 1.5 Regressions 1.6 Properties of Least-squares Regressions 1.6 Regressions and Correlations 1.7 Maxim...
متن کاملGenetics of childhood disorders: XII. Genomic imprinting: breaking the rules.
Genomic imprinting refersto a process that distinguishes paternally derived chromosomes from maternally derived chromosomes. Imprinting plays a critical role in gene expression, mammalian development, and human disease. However, the biological requirement for imprinting remains a mystery. In the first 2 columns on the topic, we will reviewhow imprinting was initially identified, present some hy...
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ژورنال
عنوان ژورنال: Genetics
سال: 2018
ISSN: 1943-2631
DOI: 10.1534/genetics.118.301373